How Depression affects Coronary Heart Disease

Depression is now considered a major health problem, particularly those health problems related to heart disease. It is now important to recognize that depression is directly linked with heart disease. Depression is an illness that can affect anyone at any time.

Research shows that depression is extremely common with people who have coronary heart disease. Depression is known to increase the risk of further heart problems in people with coronary disease. Depression is a risk factor for coronary

Drug Addiction: A Disease

Drug addiction is a disease. There’s no doubt about that. In fact experts say that drug addiction is more of a brain disease than anything else. Scientific advances have offered amazing insights into how the brain works and what drugs do to the way the brain functions. Luckily, however, this disease is treatable and curable.

Do You Have A Sexually Transmitted Disease

Some of the most uttered and regretted words that any teenager can say are, “It won’t happen to me.” As we grow into adulthood, we are bound to make some mistakes that we would never dream of making ten years later, but that does not mean anything when the choices are right in front of us. Teens can make mistakes, but some of them are larger than the others. One thing that many get when they are having sex before they should be would be a sexually transmitted disease. The problem with some is that they are very hard to see right away.

One of the most common that affects women is HPV. This is a sexually transmitted disease that is spread through genital contact, and can remain dormant in a man for a very long time. He won’t have any signs of it even when the girl does. This is also known as genital warts, because there are sores that can look like warts that appear. These can be mistaken for herpes in some if they do not know what they are looking for. The worst thing about this sexually transmitted disease is that it can cause cancer of the cervix.

Herpes is a sexually transmitted disease that confuses many. The open sores usually send someone to the doctor, but they often have no idea what this really is. When you have herpes, your life is going to be different from then on out. Some think they can only pass this sexually transmitted disease along when they are having a out-break, but that has been proven to be untrue. It can go from person to person through sexual contact at any time. There are some good medications out for this now, but nothing is foolproof at this point.

Probably one of the worst sexually transmitted disease is HIV-AIDS. Though people are living a lot longer with this disease now, it is still not something that anyone should mess with. There are some that think this is a disease that affects the gay community only, or that it is only something that you have to worry about if you live in urban areas. Both are wrong. You don’t want to get this sexually transmitted disease, so think about that before you take another step. If for any reason you think you have been exposed to any of these, see someone right away.

Vulnerable Plaque in Heart Disease

Swelling (inflammation) is the body's natural reaction to an injury. Inflammation can happen anywhere on the skin, within the body, and even inside the arteries. Scientists are now learning inflammation may play a part in many of the diseases that come with aging, including coronary artery disease.

For many years, doctors have thought that the main cause of a heart attack or stroke or was the buildup of fatty plaque within an artery, leading to the heart or brain. In time, the plaque buildup would narrow the artery so much, that the artery would close off or become clogged by a blood clot. The lack of oxygen-rich blood to the heart would then lead to a heart attack. However these types of blockages cause only about 3 out of 10 heart attacks.

Researchers are finding people who that heart attacks do not have arteries severely narrowed by plaque! Vulnerable plaque may be buried inside the artery wall, and not bulge out and block the blood flow through the artery. This is why researchers began to look at how inflammation affects the arteries, and to see if inflammation could lead to a heart attack.

What they found was that inflammation leads to the development of "soft" or vulnerable plaque. They also found that vulnerable plaque was more than just debris, clogging an artery, that it was filled with different cell types that help with blood clotting.

When this inflammation is combined with other stresses, like high blood pressure, it can cause the thin covering over the plaque to crack and bleed, spilling the entire contents of the vulnerable plaque into the bloodstream. The sticky cytokines on the artery wall capture blood cells (mainly platelets) that rush to the site of injury. When these cells clump together, they can form a clot large enough to block the artery

EARLY DETECTION OF DISEASE IN THE CHILD.

It is highly important that a mother should possess such information as will enable her to detect disease at its first appearance, and thus insure for her child timely medical assistance. This knowledge it will not be difficult for her to obtain. She has only to bear in mind what are the indications which constitute health, and she will at once see that all deviations from it must denote the presence of disorder, if not of actual disease. With these changes she must to a certain extent make herself acquainted.

Signs of health.

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The signs of health are to be found, first, in the healthy performance of the various functions of the body; the regular demands made for its supply, neither in excess or deficiency; and a similar regularity in its excretions both in quantity and appearance.

If the figure of the healthy infant is observed, something may be learnt from this. There will be perceived such an universal roundness in all parts of the child's body, that there is no such thing as an angle to be found in the whole figure; whether the limbs are bent or straight, every line forms a portion of a circle. The limbs will feel firm and solid, and unless they are bent, the joints cannot be discovered.

The tongue, even in health, is always white, but it will be free from sores, the skin cool, the eye bright, the complexion clear, the head cool, and the abdomen not projecting too far, the breathing regular, and without effort.

When awake, the infant will be cheerful and sprightly, and, loving to be played with, will often break out into its merry, happy, laugh; whilst, on the other hand, when asleep, it will appear calm, every feature composed, its countenance displaying an expression of happiness, and frequently, perhaps, lit up with a smile.

Just in proportion as the above appearances are present and entire, health may be said to exist; and just in proportion to their partial or total absence disease will have usurped its place.

We will, however, for the sake of clearness examine the signs of disease as they are manifested separately by the countenance, the gestures, in sleep, in the stools, and by the breathing and cough.

Of the countenance.

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In health the countenance of a thild is expressive of serenity in mind and body; but if the child be unwell, this expression will be changed, and in a manner which, to a certain extent, will indicate what part of the system is at fault.

The brows will be contracted, if there is pain, and its seat is in the head. This is frequently the very first outward sign of any thing being wrong, and will occur at the very onset of disease; if therefore remarked at an early period, and proper remedies used, its notice may prevent one of the most fearful of infantile complaints "Water in the Head."

If this sign is passed by unheeded, and the above disease be threatened, soon the eyes will become fixed and staring, the head hot, and moved uneasily from side to side upon the pillow, or lie heavily upon the nurse's arm, the child will start in its sleep, grinding its teeth, and awake alarmed and screaming, its face will be flushed, particularly the cheeks (as if rouged), its hands hot, but feet cold, its bowels obstinately costive, or its motions scanty, dark-coloured, and foul.

If the lips are drawn apart, so as to show the teeth or gums, the seat of the pain is in the belly. This sign, however, will only be present during the actual existence of suffering; if, therefore, there be any doubt whether it exist, press upon the stomach, and watch the eifect on the expression of the countenance.

If the pain arise simply from irritation of the bowels excited from indigestion, it will be temporary, and the sign will go and come just as the spasm may occur, and slight remedial measures will give relief.

If, however, the disease be more serious, and inflammation ensue, this sign will be more constantly present, and soon the countenance will become pale, or sallow and sunken, the child will dread motion, and lie upon its back with the knees bent up to the belly, the tongue will be loaded, and in breathing, while the chest will be seen to heave with more than usual effort, the muscles of the belly will remain perfectly quiescent.

If the nostrils are drawn upwards and in quick motion, pain exists in the chest. This sign, however, will generally be the accompaniment of inflammation of the chest, in which case the countenance will be discoloured, the eyes more or less staring, and the breathing will be difficult and hurried; and if the child's mode of respiring be watched, the chest will be observed to be unmoved, while the belly quickly heaves with every inspiration.

Convulsions are generally preceded by some changes in the countenance. The upper lip will be drawn up, and is occasionally bluish or livid. Then there may be slight squinting, or a singular rotation of the eye upon its own axis; alternate flushing or paleness of the face; and sudden animation followed by languor.

These signs will sometimes manifest themselves many hours, nay days, before the attack occurs; may be looked upon as premonitory; and if timely noticed, and suitable medical aid resorted to, the occurrence of a fit may be altogether prevented.

The state of the eyes should always be attended to. In health they are clear and bright, but in disease they become dull, and give a heavy appearance to the countenance; though after long continued irritation they will assume a degree of quickness which is very remarkable, and a sort of pearly brightness which is better known from observation than it can be from description.

The direction of the eyes, too, should be regarded, for from this we may learn something. When the infant is first brought to the light, both eyes are scarcely ever directed to the same object: this occurs without any tendency to disease, and merely proves, that regarding one object with both eyes is only an acquired habit. But when the child has come to that age when the eyes are by habit directed to the same object, and afterwards it loses that power, this circumstance alone may be looked upon as a frequent prelude to disease affecting the head.

Of the gestures.

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The gestures of a healthy child are all easy and natural; but in sickness those deviations occur, which alone will often denote the nature of the disease.

Suppose an infant to have acquired the power to support itself, to hold its head erect; let sickness come, its head will droop immediately, and this power will be lost, only to be regained with the return of health; and during the interval every posture and movement will be that of languor.

The little one that has just taught itself to run alone from chair to chair, having two or three teeth pressing upon and irritating the gums, will for a time be completely taken off its feet, and perhaps lie languidly in its cot, or on its nurse's arm.

The legs being drawn up to the belly, and accompanied by crying, are proofs of disorder and pain in the bowels. Press upon this part, and your pressure will increase the pain. Look to the secretions from the bowels themselves, and by their unhealthy character your suspicions, in reference to the seat of the disorder, are at once confirmed.

The hands of a child in health are rarely carried above its mouth; but let there be any thing wrong about the head and pain present, and the little one's hands will be constantly raised to the head and face.

Sudden starting when awake, as also during sleep, though it occur from trifling causes, should never be disregarded. It is frequently connected with approaching disorder of the brain. It may forebode a convulsive fit, and such suspicion is confirmed, if you find the thumb of the child drawn in and firmly pressed upon the palm, with the fingers so compressed upon it, that the hand cannot be forced open without difficulty. The same condition will exist in the toes, but not to so great a degree; there may also be a puffy state of the back of the hands and feet, and both foot and wrist bent downwards.

There are other and milder signs threatening convulsions and connected with gesture, which should be regarded: the head being drawn rigidly backwards, an arm fixed firmly to the side, or near to it, as also one of the legs drawn stifly upwards. These signs, as also those enumerated above, are confirmed beyond all doubt, if there be present certain alterations in the usual habits of the child: if the sleep is disturbed, if there be frequent fits of crying, great peevishness of temper, the countenance alternately flushed and pale, sudden animation followed by as sudden a fit of languor, catchings of the breath followed by a long and deep inspiration, all so many premonitory symptoms of an approaching attack.

Of the sleep.

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The sleep of the infant in health is quiet, composed, and refreshing. In very early infancy, when not at the breast, it is for the most part asleep in its cot; and although as the months advance it sleeps less, yet when the hour for repose arrives, the child is no sooner laid down to rest, than it drops off into a quiet, peaceful slumber.

Not so, if ill. Frequently it will be unwilling to be put into its cot at all, and the nurse will be obliged to take the infant in her arms; it will then sleep but for a short time, and in a restless and disturbed manner.

If it suffer pain, however slight, the countenance will indicate it; and, as when awake, so now, if there is any thing wrong about the head, the contraction of the eye-brow and grinding of the teeth will appear; if any thing wrong about the belly, the lips will be drawn apart, showing the teeth or gums, and in both instances there will be great restlessness and frequent startings.

Of the stools.

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In the new-born infant the motions are dark coloured, very much like pitch both in consistence and appearance. The first milk, however, secreted in the mother's breast, acts as an aperient upon the infant's bowels, and thus in about four-and-twenty hours it is cleansed away.

From this time, and through the whole of infancy, the stools will be of a lightish yellow colour, the consistence of thin mustard, having little smell, smooth in appearance, and therefore free from lumps or white curded matter, and passed without pain or any considerable quantity of wind. And as long as the child is in health, it will have daily two or three, or even four, of these evacuations. But as it grows older, they will not be quite so frequent; they will become darker in colour, and more solid, though not so much so as in the adult.

Any deviation, then, from the above characters, is of course a sign of something wrong; and as a deranged condition of the bowels is frequently the first indication we have of coming disease, the nurse should daily be directed to watch the evacuations. Their appearance, colour, and the manner in which discharged, are the points principally to be looked to. If the stools have a very curdy appearance, or are too liquid, or green, or dark-coloured, or smell badly, they are unnatural. And in reference to the manner in which they are discharged, it should be borne in mind, that, in a healthy child, the motion is passed with but little wind, and as if squeezed out, but in disease, it will be thrown out with considerable force, which is a sign of great irritation. The number, too, of stools passed within the four-and- twenty hours it is important to note, so that if the child does not have its accustomed relief, (and it must not be forgotten that children, although in perfect health, differ as to the precise number,)

Of the breathing and cough

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The breathing of a child in health is formed of equal inspirations and expirations, and it breathes quietly, regularly, inaudibly, and without effort. But let inflammation of the air-tubes or lungs take place, and the inspiration will become in a few hours so quickened and hurried, and perhaps audible, that the attention has only to be directed to the circumstance to be at once perceived.

Now all changes which occur in the breathing from its healthy standard, however slight the shades of difference may be, it is most important should be noticed early. For many of the complaints in the chest, although very formidable in their character, if only seen early by the medical man, may be arrested in their progress; but otherwise, may be beyond the control of art. A parent, therefore, should make herself familiar with the breathing of her child in health, and she will readily mark any change which may arise.

Whenever a child has the symptoms of a common cold, attended by hoarseness and a rough cough, always look upon it with suspicion, and never neglect seeking a medical opinion. Hoarseness does not usually attend a common cold in the child, and these symptoms may be premonitory of an attack of "croup;" a disease excessively rapid in its progress, and which, from the importance of the parts affected, carrying on, as they do, a function indispensably necessary to life, requires the most prompt and decided treatment.

The following observations of Dr. Cheyne are so strikingly illustrative, and so pertinent to my present purpose, that I cannot refrain inserting them: "In the approach of an attack of croup, which almost always takes place in the evening, probably of a day during which the child has been exposed to the weather, and often after catarrhal symptoms have existed for several days, he may be observed to be excited, in variable spirits, more ready than usual to laugh than to cry, a little flushed, occasionally coughing, the sound of the cough being rough, like that which attends the catarrhal stage of the measles. More generally, however, the patient has been for some time in bed and asleep, before the nature of the disease with which he is threatened is apparent; then, perhaps, without waking, he gives a very unusual cough, well known to any one who has witnessed an attack of the croup; it rings as if the child had coughed through a brazen trumpet; it is truly a tussis clangosa; it penetrates the walls and floor of the apartment, and startles the experienced mother, 'Oh! I am afraid our child is taking the croup!' She runs to the nursery, finds her child sleeping softly, and hopes she may be mistaken. But remaining to tend him, before long the ringing cough, a single cough, is repeated again and again; the patient is roused, and then a new symptom is remarked; the sound of his voice is changed; puling, and as if the throat were swelled, it corresponds with the cough," etc.

How important that a mother should be acquainted with the above signs of one of the most terrific complaints to which childhood is subject; for, if she only send for medical assistance during its first stage, the treatment will be almost invariably successful; whereas, if this "golden opportunity" is lost, this disease will seldom yield to the influence of measures, however wisely chosen or perseveringly employed.

Peripheral Vascular Disease

What is peripheral vascular disease?

Peripheral artery disease (PAD) is a heart condition similar to that of coronary artery disease and carotid artery disease. In PAD, the fatty deposits build up in the inner linings of the artery walls. These blockages restrict the blood flow circulation, mainly in arteries leading to the kidneys, stomach, arms, legs and feet.

In its early stages, a common symptom is cramping, or fatigue in the legs and buttocks during activity. Such cramping subsides when the person stands still. This is called "intermittent claudication." People with PAD often have fatty buildup in the arteries of the heart and brain. Because of this association, most people with PAD have a higher risk of death from heart attack and stroke.

There are two types of these circulation disorders:

Functional peripheral vascular diseases don't have an organic cause. They don't involve defects in blood vessels' structure. They're usually short-term effects related to "spasm" that may come and go. Raynaud's disease is an example. It can be triggered by cold temperatures, emotional stress, working with vibrating machinery or smoking.

Organic peripheral vascular diseases are caused by structural changes in the blood vessels, such as inflammation and tissue damage. Peripheral artery disease is an example. It's caused by fatty buildups in arteries that block normal blood flow.

How is peripheral artery disease diagnosed and treated?

Techniques used to diagnose PAD include a medical history, physical exam, ultrasound, X-ray angiography and magnetic resonance imaging angiography (MRA).

Most people with PAD can be treated with lifestyle changes, medications or both. Lifestyle changes to lower your risk include stopping smoking, diabetes control and blood pressure. Become physically active; eat a low-saturated-fat, low-cholesterol diet.

PAD may require drug treatment, too. Drugs include medicines to help improve walking distance, antiplatelet agents and cholesterol-lowering agents (statins).

Parkinson’s Disease

First described as ``shaking palsy'' the disease that now bears his name, medical science has thus far been unable to unravel the cause or causes of most Parkinson's cases or to devise a cure. Nonetheless, dramatic progress has been made in treating the disease, which is known to afflict about half a million older Americans, or one person in 100 over age 50. This figure does not include the untold thousands with symptoms of the disease that are not severe enough to prompt them to seek a diagnosis. But early diagnosis is important.

Diagnosis of Parkinson's disease is based on the patient's symptoms and performance on certain neurological and neuropsychological tests, along with ruling out other possible causes of those symptoms. Some cases of what doctors call Parkinsonism are caused by potent drugs used in the treatment of schizophrenia and other psychiatric illnesses or they are a result of poisoning by manganese.

Through medication, exercise regimens and tips on adaptive living measures, modern treatment can forestall or reduce the symptoms of Parkinson's disease, allowing patients to lead full and active lives for years after diagnosis and often for the rest of their lives because most of its victims are elderly. The late stages of the disease, however, can leave patients vulnerable to pneumonia, blood clots and bodywide infections that can be fatal.

Yoga has a major role in management of Parkinson's as it has emerged as a beneficial alternative therapy and an ideal form of exercise for Parkinson's patients because of its slow movements. Following the steps mentioned below could effectively help people with Parkinson’s:

Concentrate on controlling your breath (Pranayama) as this form of yoga helps in moments of panic – such as feet sticking to the floor when walking.

In this form of yoga, the mind is always alert.

Few yoga exercises like back strengthening postures, lots of shoulder movements, breathing practices and some meditation definitely helps.

One of the most useful forms of yoga used for Parkinson’s is Ashtanga Yoga. It works to strengthen the body and do increases blood circulation.

Daily practice of yoga is essential since Parkinson’s itself does not necessarily weaken the muscles. Weakening of muscles is generally caused by lack of movement. Daily practice should be encouraged, but not enough to cause fatigue.

Parkinson’s also result in the loss of movement of the facial muscles. Pranayama and other yoga movements could help in relaxing those muscles and bring in smile on the faces of the patient.

Periodontal Disease in Adolescents

The meaning of the word “periodontal” is around the tooth. Also known as gum diseases periodontal diseases are nothing but serious infections caused by bacteria that harm the gums and tissues in the vicinity of the mouth. While dental cavities or caries only affects the tooth Periodontal disease is devastating affecting the bones that surround the tooth, gums, coverings of teeth root and tooth membrane. A physician specializing in the treatment of periodontal disease is known as Periodontist.

The disease should not be taken lightly and if it’s left untreated it can spread and affect the bones under the teeth which would eventually dissolve and would not longer support the teeth in its place. The chronic form of the disease is responsible for tooth loss in seventy percent of the cases affecting seventy five percent of the people at some time in their lives.

The causes of periodontal disease are similar to any other oral disease wherein plaque buildup and bacteria are responsible for the condition. According to statistics plaque buildup is the main cause of gum related diseases. Apart from the causes listed, the other possible causes of periodontal disease include: Genetics, unkempt oral hygiene, food getting stuck to frequently in the gums, mouth breathing, low nutrient diet or vitamin c deficient diet, smoking, diabetes, autoimmune/systemic disease, changes in hormone levels, certain medications and constantly teeth grinding.

According to statistics nearly sixty six percent young adult population suffers from periodontal disease and nearly fifty percent of teenagers suffer from periodontal disease. Also, it is the most widespread tooth loss cause in adults. But, what are the symptoms of periodontal disease? There are various symptoms and it could differ from one adolescent to the other which may include swollen, tender, and red gums; if one gets bleeding during brushing or flossing the teeth it is also one of the symptoms of periodontal disease; receding gums; constant odorous breath; loose teeth; dentures not fitting any longer; change in alignment of jaw and bite. The symptoms of the disease may be similar to other medical conditions and doctor’s consultation is the best in this regard.

Periodontal disease can be diagnosed by a dentist or a periodontist after reviewing the complete medical history and also physical examination of the teenager’s mouth. Usually x-ray of the teeth is taken to evaluate the disease. Periodontal disease is classified into different types based on what stage the disease is in. The mildest form of gum disease is known as “gingivitis” in which gums become swollen, red and tender resulting in bleeding while daily brushing and flossing. Gingivitis is again divided into 4 groups primarily acute, sub-acute, recurrent and chronic. Acute gingivitis is nothing but sudden appearance which lasts for shorter duration and could be painful. Sub-acute gingivitis is less severe type of gingivitis. Recurrent gingivitis is the one that comes back after treatment. Chronic gingivitis is the one that onsets slowly, lasts longer and is generally painless. A dentist’s treatment and proper and continuous care can easily solve the problem of gingivitis but if left untreated could result in periodontitis.

Periodontitis is further classified into mild and moderate to advance. Periodontitis results from untreated gingivitis. In this stage the deterioration of the bone in the vicinity of the tooth becomes evident. The common symptoms include red gums that bleed; mouth tastes bad; loose teeth; tooth loss. Proper treatment is a must to control the disease and prevent further deterioration. Periondontitis which is in moderate to advanced stage shows signs of major loss of tissue and bone loss near the teeth.

There are various treatments available for periodontal disease which is decided by the dentist depending on teenager’s age, medical history and health in general. The method of treatment also depends on the extent to which disease has reached. The tolerance of the teenager to certain medicines, therapies and procedures are also taken into consideration. Expectations and opinion of the parents or teenager is also the criteria in deciding the type of treatment. The treatment usually involves plaque removal, medication and in worse cases a surgery.

Eye And Heart Disease

Eye disease is very common with Golden Retrievers. Most Golden’s will generally have hereditary cataracts, which is a common eye problem. At an early age, with affected Golden’s, one type of hereditary cataract will appear. Even though it may not cause interference with the vision of the Golden Retriever, some dogs will progress into total and quite possibly severe loss of vision.

Sometimes, Golden Retrievers can get affected by non hereditary cataracts, although an examination by a board certified veterinarian can determine just how bad the cataracts really are. If cataracts are indeed suspected with a Golden Retriever, then breeding won’t be recommended. Breeding a Golden who has this condition can lead to serious problems, such as passing it on to the pups.

Several families of the Golden Retriever breed have been known to carry genes for CPRA (Central Progressive Retinal Atrophy), which affects the retina, and can result in permanent blindness for Golden’s at a young age. There are other types of eye defects as well, such as retinal dysplasia, which prevents a Golden from breeding.

Trouble with both the eyelid and eyelashes are also a possibility with Golden Retrievers, with some being the result of hereditary factors. The eyelids rotating in or out, or the eyelashes rubbing on or in the eye are both common problems with the breed. Even though surgery can help to fix these types of problems, dogs that are experiencing this type of problem shouldn’t be allowed to breed nor compete in shows under any type of AKC rules.

You should always have your Golden Retriever checked annually for eye disease, as it can develop during any age. When you take your Golden to have him examined for eye disease, you should have a veterinary ophthalmologist do the exam. He has all of the necessary equipment, and the proper training needed to make sure that your dog gets the best examination possible.

Heart disease

SAS (Subvalvular Aortic Stenosis) is the most common and widespread form of heart disease within the entire Golden Retriever species. Before you breed your Golden Retriever, you should always have him examined for heart disease by a certified veterinary cardiologist. If the cardiologist detects a heart murmur, he will recommend additional tests for your dog.

In the event that the results prove negative, it doesn’t necessarily rule heart disease out, as some milder forms may still be present, although undetectable. If a Golden Retriever is diagnosed to have any type of heart disease, he should not breed. Breeding Golden Retrievers who have heart disease can lead to serious and sometimes fatal results. To be on the safe side, you should always have your Golden tested for his disease before you plan on breeding.

Women and Heart Disease

Heart diseases are common among the women population just as is the case in male population. In fact, it is estimated that 8.6 million women succumb to the illness annually in the United States alone. This means that the disease is responsible for a third of all women deaths in the country. Women heart disease is currently affecting eight million women, with 35,000 of these being under 65 years of age. Another four million are angina sufferers.

The prevalence of women heart disease is evident in the 435,000 heart attacks registered annually in the different parts of the country. Statistics indicate that 42 percent of the heart attack suffers die within a year of the attack. This means that women who suffer heart attacks die at a faster rate than men. Statistics in the trend of heart ailments in men indicate that only 24 percent of men die a year after suffering an initial heart attack.

Women heart diseases first presents with mild symptoms which feel like flu to most women. According to health professionals, at least 71 percent of women with heart conditions experience these mild symptoms, which usually manifest as extreme weakness. At this early stage, most women do not have pains in the chest. In fact, health statistics indicate that about two-thirds of heart related deaths occur in women who have never had chest pains before.

Just like in the male population, the most profound women heart disease risk factors include tobacco smoking, abnormal amounts of lipids in the blood and diabetes. Previous researches indicate that women smokers increase their risk by 19 years compared to non smokers. Hypertension, which is common in people using the oral contraceptive, also increases the chance of women developing heart disease. Diabetes on the other hand places women sufferers on twice the risk of suffering from women heart disease when compared to the non-diabetics. More so, diabetes places women at double the risk of repeat heart attacks.

The diagnosis for women heart disease is not as straight forward as is the case with men. This is attributed to the even distribution of plaque in women’s arteries, which passes as normal in angiographic studies. In men however, the plaque clumps in different areas of the artery walls thus leading to easy diagnosis.

However, it is not all doom for women heart disease sufferers. Studies have shown that the female heart is able to respond better to lifestyle changes than does the male heart. As such, women can easily adopt lifestyle changes related preventive measures to keep the disease at bay.

NAILS IN HEALTH AND DISEASE.

Introduction:

The nails are present at the end of each finger tip on the dorsal surface.The main function of nail is protection and it also helps for a firm grip for holding articles.It consists of a strong relatively flexible keratinous nail plate originating from the nail matrix. Under the nail plate there is a soft tissue called nail bed.Between the skin and nail plate there is a nail fold or cuticle.Normal healthy nail is slight pink in colour and the surface is convex from side to side.Finger nails grow 1 cm in three months and toe nails take 24 months for the same.

Importance of nails in disease diagnosis:

The colour ,appearance, shape and nature of the nails give some information about the general health and hygiene of a person . Nails are examined as a routine by all doctors to get some clues about underlying diseases.Just looking at nails we can makeout the hygiene of a person.The abnormal nail may be congenital or due to some diseases.The cause for changes in the nail extend from simple reasons to life threatening diseases.Hence the examination by a doctor is essential for diagnosis .Some abnormal findings with probable causes are discussed here for general awareness.

1) Hygiene:-

We can make out an unhygienic nail very easily .Deposition of dirt under the distal end of nail plate can make a chance for ingestion of pathogens while eating.If nail cutting is not done properly it can result in worm troubles in children.When the worms crawl in the anal orifice children will scratch which lodges the ova of worms under the nails and will be taken in while eating.Prominent nail can also complicate a skin disease by habitual scratching.Sharp nails in small kids cause small wounds when they do feet kicking or hand waving.

2) Colour of the nails:-

a) Nails become pale in anaemia.

b) Opaque white discolouration(leuconychia) is seen in chronic renal failure and nephrotic syndrome.

c) Whitening is also seen in hypoalbuminaemia as in cirrhosis and kidney disorders.

d) Drugs like sulpha group,anti malarial and antibiotics ect can produce discolouration in the nails.

e) Fungal infection causes black discolouration.

f) In pseudomonas infection nails become black or green.

g) Nail bed infarction occures in vasculitis especially in SLE and polyarteritis.

h) Red dots are seen in nails due to splinter haemorrhages in subacute bacterial endo carditis, rheumatoid arthritis, trauma, collagen vascular diseases.

i) Blunt injury produces haemorrhage and causes blue/black discolouration.

j) Nails become brown in kidney diseases and in decreased adrenal activity.

k) In wilsons disease blue colour in semicircle appears in the nail.

l) When the blood supply decreases nail become yellow .In jaundice and psoriasis also nail become yellowish.

m) In yellow nail syndrome all nails become yellowish with pleural effusion.

3) Shape of nails:-

a) Clubbing: Here tissues at the base of nails are thickened and the angle between the nail base and the skin is obliterated. The nail becomes more convex and the finger tip becomes bulbous and looks like an end of a drumstick. When the condition becomes worse the nail looks like a parrot beak.

Causes of clubbing:-

Congenital Injuries

Severe chronic cyanosis

Lung diseases like empyema,bronchiactesis,carcinoma of bronchus and pulmonary tuberculosis.

Abdominal diseases like crohn's disease,polyposis of colon,ulcerative colitis,liver cirrhosis ect...

Heart diseases like fallot's tetralogy,subacute bacterial endocarditis and ect..

b) Koilonychia:-

Here the nails become concave like a spoon.This condition is seen in iron deficiency anaemia.In this condition the nails become thin,soft and brittle.The normal convexity will be replaced by concavity.

c) Longitudinal ridging is seen in raynaud's disease.

d) Cuticle becomes ragged in dermatomyositis.

e) Nail fold telangiectasia is a sign in dermatomyositis ,systemic sclerosis and SLE.

4) Structure and consistancy:-

a) Fungal infection of nail causes discolouration,deformity,hypertrophy and abnormal brittleness.

b) Thimble pitting of nail is charecteristic of psoriasis ,acute eczema and alopecia aereata.

c) The inflamation of cuticle or nail fold is called paronychia.

d) Onycholysis is the seperation of nail bed seen in psoriasis,infection and after taking tetracyclines.

e) Destruction of nail is seen in lichen planus,epidermolysis bullosa.

f) Missing nail is seen in nail patella syndrome.It is a hereditary disease.

g) Nails become brittle in raynauds disease and gangrene.

h) Falling of nail is seen in fungal infection,psoriasis and thyroid diseases.

5) Growth:-

Reduction in blood supply affects the growth of nails. Nail growth is also affected in severe ilness. when the disease disappears the growth starts again resulting in formation of transverse ridges.These lines are called Beau's lines and are healpful to date the onset of illness.

Heart disease : Facts

Heart disease is a term that applies to a large number of medical conditions relating to the heart. These medical conditions relate to the abnormal health conditions that directly affect the heart and all its components. Heart disease is a major health problem within some cultures.

One theory for heart disease is the radical changes within our lifestyles. People are often less active and eat diets high in fats. Takeaway food is abundant today and often people will eat it due to the increased availability. Some takeaway outlets are now helping cater to a healthier lifestyle by offering a variety of healthy dishes such as salads. People are becoming more aware of the risk of heart disease and choosing to change their diets.

Exercise is extremely important in order to avoid heart disease. Exercise helps to keep the heart in peak performance. By using a combination of exercise and a balanced diet, the risk of heart disease is greatly decreased.

The term Cardiovascular Disease covers a large number of diseases that directly affect the heart and the blood vessel system. It especially affects the veins and arteries that lead to and from the heart. Research has suggested that women who suffer with cardiovascular disease usually suffer from forms that affect the blood vessels. While men usually suffer from forms that affect the heart muscle itself. Other known or associated causes of cardiovascular disease include diabetes mellitus, hypertension and hypercholesterolemia.

Heart disease and strokes are other common cardiovascular diseases. Two independent risk factors that have a major impact for heart diseases, cardiovascular diseases, are high blood pressure and high blood cholesterol.

Now day’s heart disease does not have to be a death sentence. There are healthy lifestyle choices that can be made and science has come a long way in the early detection of heart disease.

A study finds that HIV-Infected Men at Increased Risk for Heart Disease

NIH-supported research also identifies predictors of heart disease risk in this group

The buildup of soft plaque in arteries that nourish the heart is more common and extensive in HIV-infected men than HIV-uninfected men, independent of established cardiovascular disease risk factors, according to a new study by National Institutes of Health grantees. The findings suggest that HIV-infected men are at greater risk for a heart attack than their HIV-uninfected peers, the researchers write in Annals of Internal Medicine.

In addition, blockage in a coronary artery was most common among HIV-infected men whose immune health had declined the most over the course of their infection and who had taken anti-HIV drugs the longest, the scientists found, placing these men at even higher risk for a heart attack.
“These findings from the largest study of its kind tell us that men with HIV infection are at increased risk for the development of coronary artery disease and should discuss with a care provider the potential need for cardiovascular risk factor screening and appropriate risk reduction strategies,” said Gary H. Gibbons, M.D., director of the National Heart, Lung, and Blood Institute (NHLBI), part of NIH.

“Thanks to effective treatments, many people with HIV infection are living into their 50s and well beyond and are dying of non-AIDS-related causes—frequently, heart disease,” said Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), also part of NIH. “Consequently, the prevention and treatment of non-infectious chronic diseases in people with HIV infection has become an increasingly important focus of our research.”

NIAID and NHLBI funded the study with additional support from the National Center for Advancing Translational Sciences, part of NIH.

Past studies of the association between heart disease and HIV infection have reached inconsistent conclusions. To help clarify whether an association exists, the current investigation drew participants from the Multicenter AIDS Cohort Study (MACS), a study of HIV/AIDS in gay and bisexual men established by NIAID nearly 30 years ago.

“One advantage of the MACS is that it includes HIV-uninfected men who are similar to the HIV-infected men in the study in their sexual orientation, lifestyle, socioeconomic status and risk behavior, which makes for a good comparison group,” said Wendy S. Post, M.D., who led the study. Dr. Post is a professor of medicine and epidemiology at the Johns Hopkins School of Medicine and the Johns Hopkins Bloomberg School of Public Health in Baltimore.

Another advantage was the MACS’ size, with nearly 7,000 men cumulatively enrolled, 1,001 of whom participated in the new study. The participants included 618 men who were HIV-infected and 383 who were not. All were 40 to 70 years of age, weighed less than 200 pounds, and had had no prior surgery to restore blood flow to the coronary arteries.

Dr. Post and colleagues investigated whether the prevalence and extent of plaque buildup in coronary arteries, a condition called coronary atherosclerosis, is greater in HIV-infected men than HIV-uninfected men and whether that plaque is soft or hard. Coronary atherosclerosis, especially soft plaque, is more likely to be a precursor of heart attack than hard plaque.

The scientists found coronary atherosclerosis due to soft plaque in 63 percent of the HIV-infected men and 53 percent of the HIV-uninfected men. After adjusting for cardiovascular disease risk factors, including high blood pressure, diabetes, high cholesterol, high body mass index and smoking, the presence of soft plaque and the cumulative size of individual soft plaques were significantly greater in men with HIV infection.

In addition, by examining a subgroup of HIV-infected men, the scientists discovered two predictors of advanced atherosclerosis in this population. The first predictor deals with white blood cells called CD4+ T cells, which are the primary target of HIV and whose level, or count, is a measure of immune health. The researchers found that for every 100 cells per cubic millimeter decrease in a man’s lowest CD4+ T cell count, his risk of coronary artery blockage rose by 20 percent. The scientists also found that for every year a man had taken anti-HIV drugs, his risk of coronary artery blockage rose by 9 percent.

Because the investigators examined coronary artery plaque at a single point in time, further research is needed to determine whether coronary artery plaque in HIV-infected men is less likely to harden over time, or whether these men simply develop greater amounts of soft plaque, according to Dr. Post. In addition, she said, studies on therapies and behavioral changes to reduce risk for cardiovascular disease in men and women infected with HIV are needed to determine how best to prevent progression of atherosclerosis in this population.

The study was funded by NIH through grant numbers RO1-HL-095129, UL1-RR-025005, UO1-AI-35042, UL1-RR-025005, UM1-AI-35043, UO1-AI-35039, UO1-AI-35040, and UO1-AI-35041. The National Cancer Institute co-funds the MACS.

For more information about HIV/AIDS, please visit http://aids.gov .

NIAID conducts and supports research—at NIH, throughout the United States, and worldwide—to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at http://www.niaid.nih.gov.

Exercise, Diet May Help ' Pre-Diabetics ' Dodge Heart Disease Death

By Steven Reinberg

For people with high blood sugar at risk of type 2 diabetes, losing weight and exercising may lessen their chances of dying from heart disease or other conditions, a new long-term study suggests.

People enrolled in the study on diabetes prevention in China followed a diet and exercise program for six years, then were followed by researchers for another 23 years.

Over that time, there was a significant reduction in their risk of death from cardiovascular diseases--such as coronary heart disease and stroke--and death from other causes, the researchers found.

"This reduction in mortality appears to be due in part to the delay in the onset of diabetes resulting from the lifestyle interventions," said lead researcher Dr. Guangwei Li, of the department of endocrinology at the China-Japan Friendship Hospital, in Beijing.

For the study, Li's group randomly assigned 438 patients to the diet and exercise program, and another 138 patients to maintain their regular lifestyle.

Diets were designed to produce weight loss in obese or overweight participants, and to reduce carbs and alcohol intake in people of normal weight, the study authors explained.

The exercise segment of the program focused on increasing how much physical activity participants did during their leisure time.

After more than two decades of follow-up, the incidence of death from cardiovascular disease among those in the diet and exercise program was about 12 percent, compared with nearly 20 percent among those who did not change their lifestyles, the study found.

Moreover, the incidence of death from any cause was about 28 percent among those in the lifestyle-change group versus over 38 percent among the others, the researchers added.

Previous research has shown that for people with type 2 diabetes, the risk of dying from heart conditions and stroke is more than twice that of people without diabetes, Li noted.

"These [new] findings provide yet further justification to implement lifestyle interventions in people with high blood sugar, as clinical and public health measures to control the long-term consequences of diabetes," Li said.

The report was published April 3 in the online edition of The Lancet Diabetes & Endocrinology.

Dr. David Katz, director of the Yale University Prevention Research Center, said that "lifestyle is the best medicine has been established by an impressively consistent array of research findings spanning populations and decades."

Careful attention to eating well, being active, controlling weight and avoiding tobacco has been shown to reduce the lifetime risk of all major chronic disease by 80 percent, he said.

"This study shows first, that an intervention focused particularly on diabetes prevention has generalized benefits," Katz said. "This is not very surprising, since the causal and protective factors for all of the prevalent chronic diseases are interrelated. The same diet and activity pattern that helps prevent diabetes does the same for cardiovascular disease, "he added.

"Second, and more surprising, this study suggests that a robust lifestyle intervention program of sufficient duration is a gift that keeps on giving, conferring benefit for years after it concludes," Katz said. "This offers important promise with regard to the cost-effectiveness of such interventions."

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