CLINICAL EVALUATION
This is done by evaluating sign and symptoms of thyroid disorders or by palpation. Normal thyroid is rubbery feel; in Graves’s disease and diffused colloidal goiter it has soft consistency. In Hashimoto’s disease it is firm, in thyroid carcinoma and Riedel’s thyroiditis it is rock hard and irregular outline.
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| Doctors performing ultrasound of thyroid |
Symptoms: Increase irritability, sweating, palpitation, SOB, loss of weight, increase bowel movement, loss of appetite, etc.
Signs: Tachycardia, tremor, warm and moist peripheries, arrhythmias, etc.
Hypothyroidism:
Symptoms: Dry skin, slow speech, constipation, weight gain, dry hair and fallout, facial puffiness, angina, etc.
Signs: Pale, dry skin, goiter, cool peripheries, alopecia, bradycardia, ascites, hydrocele, etc.
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| (Courtesy: About.com, Thyroid disease) |
IN VITRO TEST OF THYROID ACTIVITY
The tests used to investigate thyroid dysfunction can be grouped into:
1. Test for thyroid dysfunction: TSH, T4, T3 measurement in serum
2. Test to identify cause of thyroid dysfunction: E.g. autoantibodies and serum TBG, thyroid enzyme activities, biopsy, etc.
3. Test to monitor treatment and detect recurrences of follicular carcinoma: TBG measurement
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